Purified anti-Gli-1

This gene encodes a protein which is a member of the Kruppel family of zinc finger proteins. The function of this gene has not been determined; however, it may play a role in normal development gene transcription. The Gli transcription factors constitute the final effectors of the Hedgehog signalling pathway, which is critical to vertebrate development. Mouse mutation studies indicate possible involvement in human foregut malformation. In addition, both the Ras and Transforming Growth Factor Beta pathways also stimulate and/or induce Gli1 and Gli2 activity independently of Hedgehog ligands.

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SPECIFICATIONS

Catalog Number

642401

Size

50 microl

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Clone

Poly6424

Antigen

Synthetic peptide

Gene Id

2735

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

Zinc finger protein GLI1, Glioma-associated oncogene

Regulatory Status

RUO