Purified anti-GCN5

GCN5 (general control of amino-acid synthesis 5) is a 94 kD member of the N-acetyltransferase superfamily. This nuclear protein is highly expressed in the liver where it functions as a transcriptional co-activator, transfering acetyl group from acetyl-CoA to epsilon amino acid of lysine 14 in core histone H3 to control chromatin remodeling during transcriptional activation. GCN5 is a component of the human STAGA transactivator complex (SPT3, TAF, and GCN5) and can be modified by phosphorylation (which inhibits activity). In addition to the STAGA complex proteins, GCN5 has been shown to interact with E1A and Myc. The Poly6073 antibody has been shown to be useful for Western blotting of the human GCN5 protein. The Poly6073 antibody is directed against the human GCN5 N-terminus.

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SPECIFICATIONS

Catalog Number

607302

Size

200 microl

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Clone

Poly6073

Antigen

Recombinant (partial) , N-terminal

Gene Id

14534

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

General control of amino-acid synthesis 5

Regulatory Status

RUO