Purified anti-Galectin-9

Galectin-9 is a mammalian lectin with a molecular weight around 40 kD. It is a member of the beta-galactoside-binding family. With two conserved carbohydrate recognition domains (CRDs), galectin-9 binds small beta-galactosides as well as complex glycoconjugates. HAVCR2/TIM3 has been reported as one of its ligands. Galectin-9 may be retained intracellularly or transported to the cell surface where it can be cleaved to generate a soluble form. Galectin-9 is expressed by lymphocytes, dendritic cells, granulocytes, eosinophils, astrocytes, endothelial cells, fibroblasts, and thymus epithelial cells. It can be induced by cytokines in various cell types and is involved in cell aggregation, adhesion, chemotaxis, and apoptosis; galectin-9 induces regulatory T cells and suppresses Th1 and Th17 responses.

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SPECIFICATIONS

Catalog Number

650702

Size

100 microg

Applications

WB

Hosts

Mouse

Reactivities

Hum

Clone

9S2-1

Antigen

Human Galectin-9 (S-type)

Gene Id

3965

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 1 microg per ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store undiluted at 4C.

Alternative Names

Lgals9, Gal-9, Ecalectin, Tumor antigen HOM-HD-21, Ecalectin

Regulatory Status

RUO