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Purified anti-DNA-PKcs Phospho (Thr2609)

Purified anti-DNA-PKcs Phospho (Thr2609)

Cat no: 612902

Supplier: BioLegend
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DNA-protein kinase catalytic subunit (DNA-PKcs) also known as DNA-activated kinase is a nuclear 460-470 kD serine threonine kinase involved in double-stranded DNA break repair, VDJ recombination, and transcriptional modulation. DNA-PKcs must bind DNA ends to become active. DNA-PKcs is modified by phosphorylation and has been shown to interact with Ku70/Ku80, KIP, DNA-ligase IV, and XRCC4 proteins. Phosphorylated DNA-PKcs is upregulated after DNA damaage. The 10B1 monoclonal antibody recognizes phosphorylated human DNA-PKcs (Thr2609) and has been shown to be useful for immunofluorescence staining and Western blotting.
Catalogue number: 612902
Reactivities: Human
Hosts: Mouse
Applications: Immunofluorescence, Western Blot
Size: 100 microg
Clone: 10B1
Gene: 19090
Dilutions: Each lot of this DNA-PKcs antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microg antibody per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1-4 microg/ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Modified peptide
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: DNA-protein kinase catalytic subunit, DNA-activated protein kinase, DNA-dependent protein kinase
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