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Purified anti-Caspase-8

Purified anti-Caspase-8

Cat no: 645501

Supplier: BioLegend
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Caspase-8 is involved in the apoptosis mediated by CD95 and TNFR-1. It is suggested that following the triggering of apoptosis by CD95 or TNFR-1, the adaptor molecule FADD interact physically with cytosolic caspase-8 and initiate the apoptotic cascade. The active caspase-8 consists of two subunits of p18 and p10. This antibody should recognize the whole length of human caspase-8 and some isofrms of lower MW.
Catalogue number: 645501
Reactivities: Human
Hosts: Rat
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 25 microg
Clone: 1H10
Gene: 841
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5-1 microg antibody per ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store at 4C.
Concentration: 0.5 mg/ml
Antigen: Full length caspase-8 fusion protein
Isotype: Rat IgG2a
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: MACH, FLICE, Mch5
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