Purified anti-Caspase 2L

Caspase 2 (Nedd-2/ICH-1) is a member of the peptidase family C14 that contains a CARD domain. This caspase has been reported to have two isoforms.The larger protein, Caspase-2L(ICH-1L) possesses proapoptotic activities , whereas Caspase-2S (ICH-1S) is able to inhibit apoptosis.When cells are induced to undergo apoptosis, endogenous Caspase 2 is probably activated early in the apoptotic process by cleaves into three fragments of 33 and 14 kD, and then these are further processed into 18 and 12 kD active subunits. The Poly6340 antibody has been shown to be useful for western blotting, immunoprecipitation, and immunohistochemistry of human, mouse, and rat caspase-2L p12 subunit and precursor (also designated Ich-1L).

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SPECIFICATIONS

Catalog Number

634001

Size

125 microl

Applications

IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Clone

Poly6340

Antigen

Peptide mapping to the carboxy terminal of human caspase-2L.

Gene Id

8795

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting suggested working dilution(s): Use 25microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C. DO NOT FREEZE.

Alternative Names

ICH-1L, CASP2L

Regulatory Status

RUO