Purified anti-C/EBP beta (2 isoforms C/EBP beta, LAP)

C/EBP beta (also known as CCAAT/enhancer-binding protein beta, interleukin 6-dependent DNA-binding protein, and nuclear factor of interleukin 6 [NF-IL6]) is a member of the basic leucine zipper C/EBP transcription factor family. C/EBP has three isoforms that include C/EBPbeta, LAP, and LIP (35 kD, 32 kD, and 20 kD, respectively). This protein is localized in the nucleus and functions as a transcription factor in immune, inflammatory, acute-phase, cytokine, collagen type I gene expression. It is upregulated by growth hormones and has been shown to interact with CEBP-alpha, CEBP-delta, CEBP-gamma, CEBP-epsilon, and CEBP-zeta. The C/EBP beta protein is known to be modified by phosphorylation and ubiquitination. The A16 monoclonal antibody has been shown to be useful for Western blotting of the mouse 35 kD and 32 kD LAP C/EBP beta isoform.

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SPECIFICATIONS

Catalog Number

626002

Size

100 microg

Applications

WB

Hosts

Mouse

Reactivities

Mouse

Clone

A16

Antigen

Recombinant full length mouse C/EBP beta protein

Gene Id

25301

Isotype

Mouse IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microg antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store at 4C.

Alternative Names

CCAAT/enhancer-binding protein beta, Alpha-1-acid glycoprotein/enhancer binding protein, Interleukin 6-dependent DNA-binding protein (IL-6DBP), Nuclear factor of interleukin 6 (NF-IL6), Liver-enriched transcriptional activator protein (LAP)

Regulatory Status

RUO