Purified anti-BAP37

BAP37, (also known as B-cell receptor-associated protein, repressor of estrogen receptor activity, and prohibitin 2) is a 37 kD erythrocyte band 7 integral membrane protein that contains an SPFH domain. BAP37 is located in the inner mitochondrial membrane that selectively potentiates the inhibitory effectiveness of antiestrogen-occupied ER. BAP37 plays a possible role in cell aging and acts as a mitochondrial protein chaperone. This protein has been shown to interact with the estrogen receptor, prohibitin, and IgM. The Poly6118 antibody has been shown to be useful for Western blotting of the human and mouse BAP37 protein.

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SPECIFICATIONS

Catalog Number

611801

Size

50 microl

Applications

IF, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Clone

Poly6118

Antigen

Recombinant (partial) , C-terminal

Gene Id

11331

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a starting dilution of 1:100. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

B-cell receptor-associated protein, Repressor of estrogen receptor activity (REA), Prohibitin 2 (Phb2)

Regulatory Status

RUO