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PTTG1IP (Human) cDNA (1ug)

PTTG1IP (Human) cDNA (1ug)


Supplier: Aviva Systems Biology Incorporated
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The ORF of human PTTG1IP is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-PTTG1IP polyclonal antibody.
Presku: ANA11670
Size: 1ug
Gene: 754
Target: The encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.