PTPN11 antibody - N-terminal region (ARP56494_P050)

This is a rabbit polyclonal antibody against PTPN11. It was validated on Western Blot by Aviva Systems Biology. At Aviva Systems Biology we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).PTPN11,protein tyrosine phosphatase, non-receptor type 11,CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; MGC14433; PTPN11,tyrosine-protein phosphatase non-receptor type 11,tyrosine-protein phosphatase non-receptor type 11,PTP-2C,OTTHUMP00000166108,protein tyrosine phosphatase-2,protein-tyrosine phosphatase 1D,protein-tyrosine phosphatase 2C

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SPECIFICATIONS

Size

50ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Format

Lyophilized powder

Presku

ARP56494_P050

Target

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Weight

68kDa

Gene Id

5781

Alternative Names

BPTP3; CFC; MGC14433; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2