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PTK6 (2H12) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252696

PTK6 (2H12) Antibody

PTK6 (Protein tyrosine kinase 6) is a 451-amino acid protein (~52kDa),Mouse,ay function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. PTK6 has been shown to undergo autophosphorylation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. E, Xenopus/Amphibian,pressed at low level in some breast tumors, but not in normal breast tissue. Also found in melanocytes, but not e, Xenopus/Amphibian,pressed in heart, brain,Porcinelacenta, lung, liver, skeletal muscle, kidney and pancreas. Overe, Xenopus/Amphibian,pression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

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SPECIFICATIONS

Catalog Number

252696

Size

0.1 ml

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human PTK6 e, Xenopus/Amphibian,pressed in E. coli.\r<br>\r<br>

Isotype

Mouse IgG2b

Accession

Q13882

Clonality

2H12B8

Additional Info

Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK; BRK; PTK6

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