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PSENEN (presenilin enhancer 2 homolog (C. elegans)) Blocking Peptide (the C terminal of PSENEN)(100ug)

PSENEN (presenilin enhancer 2 homolog (C. elegans)) Blocking Peptide (the C terminal of PSENEN)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PSENEN Antibody(ARP59439_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP59439
Size: 100ug
Weight: 12kDa
Gene: 55851
Format: Lyophilized powder
Target: Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
Alternative names: MDS033; MSTP064; PEN-2; PEN2
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