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PRPF19 (PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)) Blocking Peptide (100ug)

PRPF19 (PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PRPF19 antibody (Catalogue #: ARP43158_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP43158
Size: 100 ug
Weight: 55kDa
Gene: 27339
Format: Lyophilized powder
Target: PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM].
Alternative names: NMP200, PRP19, PSO4, UBOX4, hPSO4
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