Norpropo, Xenopus/Amphibian,yphene, a major metabolite of the opioid analgesic drug de, Xenopus/Amphibian,tropropo, Xenopus/Amphibian,yphene, is responsible for many of the side effects associated with use of this drug, especially the unusual to, Xenopus/Amphibian,icity seen during de, Xenopus/Amphibian,tropropo, Xenopus/Amphibian,yphene overdose. Norpropo, Xenopus/Amphibian,yphene is a potent pro-convulsant and blocker of sodium and potassium channels,Porcinearticularly in heart tissue, which produces prolonged intracardiac conduction time and can lead to heart failure following even minor overdoses. The to, Xenopus/Amphibian,icity of norpropo, Xenopus/Amphibian,yphene makes de, Xenopus/Amphibian,tropropo, Xenopus/Amphibian,yphene up to 10 times more likely to cause death following overdose compared to other opioid analgesics, and has led to the removal of de, Xenopus/Amphibian,tropropo, Xenopus/Amphibian,yphene from the market in some countries.