Reactivities: | Human, Mouse |
Presku: | AAP61144 |
Size: | 100ug |
Weight: | 95kDa |
Gene: | 19126 |
Format: | Lyophilized powder |
Target: | Prom1 binds cholesterol in cholesterol-containing plasma membrane microdomains. It is rroposed to play a role in apical plasma membrane organization of epithelial cells. During early during retinal development, Prom1 acts as a key regulator of disk morphogenesis. Prom1 is involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. |
Alternative names: | 4932416E19Rik; AC133; CD133; Prom; Prom-1; Proml1 |