Presku: | APL10313 |
Size: | 200ug |
Weight: | 42 |
Gene: | 5624 |
Target: | This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis. |
Alternative names: | PC; APC; PROC1; PROC |