
Supplier:
Aviva Systems Biology IncorporatedPrnp (prion protein ) Blocking Peptide (the middle region of Prnp)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum, Mouse
Format
Lyophilized powder
Presku
AAP63174
Target
Prnp may play a role in neuronal development and synaptic plasticity, may be required for neuronal myelin sheath maintenance and may play a role in iron uptake and iron homeostasis. Prnp is a soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. It also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.
Weight
28kDa
Gene Id
19122
Alternative Names
AA960666; AI325101; CD230; PrP; PrP<C>; PrPC; PrPSc; Prn-i; Prn-p; Sinc; prP27-30; prP33-35C
Applications
ELISA, FC
Hosts
Mouse
Reactivities
Hum
Applications
ELISA
Hosts
Mouse
Applications
ELISA
Hosts
Mouse
Applications
ELISA
Hosts
Mouse
Applications
ELISA
Hosts
Mouse
Applications
ELISA
Hosts
Mouse
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