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Prnp (prion protein ) Blocking Peptide (the middle region of Prnp)(100ug)

Prnp (prion protein ) Blocking Peptide (the middle region of Prnp)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Prnp Antibody (ARP63174_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP63174
Size: 100ug
Weight: 28kDa
Gene: 19122
Format: Lyophilized powder
Target: Prnp may play a role in neuronal development and synaptic plasticity, may be required for neuronal myelin sheath maintenance and may play a role in iron uptake and iron homeostasis. Prnp is a soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. It also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.
Alternative names: AA960666; AI325101; CD230; PrP; PrP; PrPC; PrPSc; Prn-i; Prn-p; Sinc; prP27-30; prP33-35C
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