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PRELP (proline/arginine-rich end leucine-rich repeat protein) Blocking Peptide (the middle region of protein) (100ug)

PRELP (proline/arginine-rich end leucine-rich repeat protein) Blocking Peptide (the middle region of protein) (100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PRELP antibody (Catalogue #: ARP56412_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP56412
Size: 100 ug
Weight: 42kDa
Gene: 5549
Format: Lyophilized powder
Target: PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
Alternative names: MGC45323; MST161; MSTP161; SLRR2A