
Supplier:
Aviva Systems Biology IncorporatedPPP4R2 antibody - C-terminal region (ARP42719_P050)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat
Format
Lyophilized powder
Presku
ARP42719_P050
Target
PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Weight
47kDa
Gene Id
151987
Alternative Names
MGC131930; PP4R2
Applications
ELISA, WB
Hosts
Mouse
Applications
IHC
Hosts
Mouse
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