PPP3R1 Human - Recombinant Human Protein Phosphatase 3, Regulatory subunit, Alpha Isozyme (5ug)

Product Introduction: PPP3R1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase which takes a vital part in the T cell activation pathway. Calcineurin is composed of two subunits; calcineurin A (CnA) and calcineurin B (CnB). Dephosphorylation of the nuclear factor of activated T-cells (NF-AT) by Calcineurin is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells.
Product Description: PPP3R1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids (1-170.a.a) and having a molecular mass of 21.5kDa. PPP3R1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.