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PPP1R12A (protein phosphatase 1, regulatory (inhibitor) subunit 12A ) Blocking Peptide (the C terminal of PPP1R12A)(100ug)

PPP1R12A (protein phosphatase 1, regulatory (inhibitor) subunit 12A ) Blocking Peptide (the C terminal of PPP1R12A)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PPP1R12A Antibody (ARP61148_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP61148
Size: 100ug
Weight: 113kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase.
Alternative names: MBS; MGC133042; MYPT1
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