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PP6C Antibody

PP6C Antibody

Cat no: 252096


Supplier: ABBIOTEC
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Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C A) is the catalytic subunit of protein phospatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PP6C A restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PP6C A downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. PP6C A is ubiquitously e, Xenopus/Amphibian,pressed in all tissues tested with highest e, Xenopus/Amphibian,pression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.
Catalogue number: 252096
Reactivities: Human, Mouse, Rabbit
Applications: Western Blot
Size: 0.1 mg
Accession: O00743
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PPP6C.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Serine/threonine-protein phosphatase 6 catalytic subunit; PP6C; PPP6C; PPP6