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POU4F3 (POU domain, class 4, transcription factor 3) Blocking Peptide (100ug)

POU4F3 (POU domain, class 4, transcription factor 3) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-POU4F3 antibody (Catalogue #: ARP33065_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP33065
Size: 100 ug
Weight: 37kDa
Gene: 5459
Format: Lyophilized powder
Target: POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
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