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POMC Human - Recombinant Human Proopiomelanocortin (2ug)

POMC Human - Recombinant Human Proopiomelanocortin (2ug)

Product Introduction: Pro-opiomelanocortin preproprotein (POMC) is a polypeptide hormone precursor which experiences extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. POMC regulates the corticosteroid production in the adrenal cortex. Furthermore, POMC is cleaved into ten hormone chains named NPP, g-MSH, ACTH, a-MSH, CLIP, Lipotropin b, Lipotropin g, b-MSH,b endorphin and Met-enkephalin. POMC gene defects are the cause of POMC deficiency, which is characterized by red hair and adrenal insufficiency.
Product Description: POMC produced in E.Coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (27-267 a.a) and having a molecular mass of 28.9kDa (molecular weight on SDS-PAGE will appear higher). POMC is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

2ug

Format

Sterile Filtered colorless solution.

Presku

OPPA00198

Alternative Names

Pro-opiomelanocortin; POMC; Corticotropin-lipotropin; LPH; MSH; NPP; POC; ACTH; CLIP.

SUPPLIER INFO

Aviva Systems Biology Incorporated

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