Polyclonal Anti-STC1

Rabbit IgG polyclonal antibody for Stanniocalcin-1 (STC1) detection. Tested with WB in Human;Mouse;Rat.

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

PA1997

Size

100ug/vial

Applications

WB

Reactivities

Hum, Mouse, Rat

Form

Lyophilized

Format

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Id

STC1

References

1. Bell, S. E., Mavila, A., Salazar, R., Bayless, K. J., Kanagala, S., Maxwell, S. A., Davis, G. E. Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. J. Cell Sci. 114: 2755-2773, 2001. \n2. Chang, A. C.-M., Jeffrey, K. J., Tokutake, Y., Shimamoto, A., Neumann, A. A., Dunham, M. A., Cha, J., Sugawara, M., Furuichi, Y., Reddel, R. R. Human stanniocalcin (STC): genomic structure, chromosomal localization, and the presence of CAG trinucleotide repeats. Genomics 47: 393-398, 1998.\n3. Wagner, G. F., Guiraudon, C. C., Milliken, C., Copp, D. H. Immunological and biological evidence for a stanniocalcin-like hormone in human kidney. Proc. Nat. Acad. Sci. 92: 1871-1875, 1995.\n4. Zhang, K., Westberg, J. A., Paetau, A., von Boguslawsky, K., Lindsberg, P., Erlander, M., Guo, H., Su, J., Olsen, H. S., Andersson, L. C. High expression of stanniocalcin in differentiated brain neurons. Am. J. Path. 153: 439-445, 1998.\n

Swiss Prot

P52823

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.

Additional Info

A synthetic peptide corresponding to a sequence in the middle region of human STC1, identical to the related rat and mouse sequences.

Scientific Background

STC1 (Stanniocalcin 1), also called STC, which is encoded by the STC1 gene. By fluorescence in situ hybridization, Chang et al. (1998) mapped the STC1 gene to chromosome 8p21-p11.2. Wagner et al. (1995) found evidence of STC immunoreactivity in human kidney and serum, suggesting the existence of the hormone in mammals. Zhang et al. (1998) reported a constitutive expression of STC in terminally differentiated neurons. Bell et al. (2001) determined that STC1 was 1 of several transcripts upregulated by umbilical vein endothelial cells during capillary morphogenesis in 3-dimensional collagen matrices.