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Polyclonal Anti-SLC7A1

Polyclonal Anti-SLC7A1

Cat no: PA2245

Supplier: Boster Immunoleader
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Rabbit IgG polyclonal antibody for High affinity cationic amino acid transporter 1 (SLC7A1) detection. Tested with WB in Human.
Catalogue number: PA2245
Price: $200.00
Reactivities: Human
Applications: Western Blot
Size: 100?g/vial
Gene: SLC7A1
Swiss prot: P30825
Form: lyophilized
Format: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Storage temp: At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing.
Scientific background: High affinity cationic amino acid transporter 1, also called solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (SLC7A1) or ATRC1 is a protein that in humans is encoded by the SLC7A1 gene. This gene is mapped to 13q12.3. It acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor and plays a role in the Na+-independent y+ cationic amino acid transport system. This gene is high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.
References: 1. Bhattacharyya, S. N., Habermacher, R., Martine, U., Closs, E. I., Filipowicz, W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125: 1111-1124, 2006. 2. Bowcock, A. M., Gerken, S. C., Barnes, R. I., Shiang, R., Jabs, E. W., Warren, A. C., Antonarakis, S., Retief, A. E., Vergnaud, G., Leppert, M., Lalouel, J.-M., White, R. L., Cavalli-Sforza, L. L. The CEPH consortium linkage map of human chromosome 13. Genomics 16: 486-496, 1993. 3. Kozak, C. A., Albritton, L. M., Cunningham, J. M. Genetic mapping of a cloned sequence responsible for susceptibility to ecotropic murine leukemia viruses. J. Virol. 64: 3119-3121, 1990.
Additional info: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC7A1, different from the related mouse and rat sequences by four amino acids.
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