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Products Polyclonal Anti-HSPBAP1
| Catalogue number: | PA1609 |
| Price: | $200.00 |
| Reactivities: | Human |
| Applications: | Western Blot |
| Size: | 100ug/vial |
| Gene: | HSPBAP1 |
| Swiss prot: | Q96EW2 |
| Form: | Lyophilized |
| Format: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time.Avoid repeated freezing and thawing. |
| Scientific background: | HSPBAP1(HEAT-SHOCK 27-KD PROTEIN-ASSOCIATED PROTEIN 1)?the other entities represented in this entry is DIRC3 FUSION GENE. HSPBAP1 shares 80% identity with the rat homolog, PASS1. The HSPBAP1 gene is mapped to chromosome 3q21.1. RT-PCR detected expression of HSPABAP1 in all tissues examined except brain. Highest expression was detected in thymus, ovary, and pancreas. The HSPBAP1 gene contains 8 exons. The putative 451-amino acid truncated HSPBAP1 protein retained its JmjC and HSP27 -interacting domains, which are associated with chromatin remodeling and stress response, respectively. |
| References: | 1.Bodmer, D., Schepens, M., Eleveld, M. J., Schoenmakers, E. F. P. M., van Kessel, A. G. Disruption of a novel gene, DIRC3, and expression of DIRC3-HSPBAPI fusion transcripts in a case of familial renal cell cancer and t(2;3)(q35;q21). Genes Chromosomes Cancer 38: 107-116, 2003. 2.Jiang, M., Ma, Y., Cheng, H., Ni, X., Guo, L., Xie, Y., Mao, Y. Molecular cloning and characterization of a novel human gene (HSPBAP1) from human fetal brain. Cytogenet. Cell Genet. 95: 48-51, 2001. |
| Additional info: | A synthetic peptide corresponding to a sequence at the N-terminal of human HSPBAP1, different from the related rat sequences by one amino acid, and different from the related mouse sequences by two amino acids. |
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