Reactivities: | Human |
Presku: | AAP57028 |
Size: | 100ug |
Weight: | 15kDa |
Gene: | 55629 |
Format: | Lyophilized powder |
Target: | PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure. |
Alternative names: | FLJ20312; MGC99541 |