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PNKP (Human) cDNA (1ug)

PNKP (Human) cDNA (1ug)


Supplier: Aviva Systems Biology Incorporated
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The ORF of human PNKP is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-PNKP polyclonal antibody.
Presku: ANA11397
Size: 1ug
Gene: 11284
Target: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.