Home  >  Products  >  PLOD2 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2) Blocking Peptide (the middle region of protein) (100ug)
PLOD2 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2) Blocking Peptide (the middle region of protein) (100ug)

PLOD2 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PLOD2 antibody (Catalogue #: ARP42731_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP42731
Size: 100 ug
Weight: 84kDa
Gene: 5352
Format: Lyophilized powder
Target: PLOD2 forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative names: LH2; TLH
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