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Platelet Derived Growth Factor A Chain (Western Blot Control) Protein (OPRB00178)

Platelet Derived Growth Factor A Chain (Western Blot Control) Protein (OPRB00178)

The term 'PDGF' refers to a family of disulphide bondlinked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets. They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family - PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist - a short form that is soluble and a long form that is retained by the extracellular matrix. . Aviva Systems Biology recombinant PDGF-A comprises a 110 amino acid fragment (87-196) corresponding to the mature PDGF-A short chain protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use

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SPECIFICATIONS

Size

10ug

Format

Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol).

Presku

OPRB00178

Alternative Names

Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-A, PDGF-1

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