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PLASMINOGEN ACTIVATOR INHIBITOR 1 (PAI-1)

Cat no: PAS9389

PLASMINOGEN ACTIVATOR INHIBITOR 1 (PAI-1)

PAI-1 is a serine protease inhibitor, which can exist either in an active inhibitory conformation or in an inactive or latent conformation. PAI-1 is produced mainly by the endothelium but is also secreted by other tissue types including adipose tissue. PAI-1 is the principal inhibitor of tissue plasminogen activator and urokinase, therefore inhibiting fibrinolysis. Increased levels of PAI-1 have been linked with various conditions including cardiovascular disease, thrombosis, insulin resistance and obesity. RANDOX recombinant PAI-1 comprises a 379 amino acid fragment (24-402) corresponding to the mature PAI-1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use

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SPECIFICATIONS

Catalog Number

PAS9389

Size

1ml

Applications

DB, ELISA, IHC, WB

Hosts

Sheep

Format

Ig fraction prepared by caprylic acid and ammonium sulphate precipitation procedures

P Type

Polyclonal

Alternative Names

PLANH1; Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; PAIE; Clade E; PLANH1; SERPINE 1

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