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PLAC3 Antibody (OAPB01193)

PLAC3 Antibody (OAPB01193)

PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB01193

Target

Pregnancy-associated plasma protein A2

Alternative Names

PLAC3; Placenta-specific protein 3; Pappalysin 2; pregnancy-associated plasma protein A2; PAPP-A2; PAPPA2

SUPPLIER INFO

Aviva Systems Biology Incorporated

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