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PIWIL1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250823

PIWIL1 Antibody

Piwi-like protein 1 (PIWIL1) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL1 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming comple, Xenopus/Amphibian,es composed of piRNAs and Piwi proteins and governing the methylation and subsequent repression of transposons. PIWIL1 binds pi RNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism. PIWIL1 is also involved in the formation of chromatoid bodies and is required for some piRNAs stability.

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SPECIFICATIONS

Catalog Number

250823

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PIWIL1.

Isotype

Rabbit Ig

Accession

Q96J94

Additional Info

Piwi-like protein 1; PIWIL1; HIWI

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