Reactivities: | Human |
Presku: | AAP38570 |
Size: | 100ug |
Weight: | 30kDa |
Gene: | 401 |
Format: | Lyophilized powder |
Target: | PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. |
Alternative names: | ARIX; CFEOM2; FEOM2; MGC52227; NCAM2; PMX2A |