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PGA5 (2C1) Antibody

PGA5 (2C1) Antibody

Cat no: 252927


Supplier: ABBIOTEC
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PGA5 (Pepsinogen 5) is an endopeptidase precursor responsible for protein digestion in the stomach. Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor,Porcineepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows e, Xenopus/Amphibian,tremely broad specificity; although bonds involving phenylalanine and leucine are preferred,Mouse,any others are also cleaved to some e, Xenopus/Amphibian,tent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.
Catalogue number: 252927
Reactivities: Human
Applications: Immunohistochemistry
Size: 0.1 ml
Accession: P0DJD9
Antigen: Purified recombinant fragment of human PGA5 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 2C1
Additional info: Pepsin A-5; Pepsinogen-5; PGA5