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PERK Antibody

PERK Antibody

Cat no: 200117

Supplier: ABBIOTEC
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PERK, a Ser/Thr protein kinase,Porcinehosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and to a rapid reduction of translational initiation and repression of global protein synthesis. PERK serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1. Defects in PERK are the cause of Wolcott-Rallison syndrome, an early-onset diabetes mellitus.
Catalogue number: 200117
Reactivities: Human, Mouse, Rabbit
Applications: Western Blot
Size: 0.1 mg
Accession: Q9NZJ5, NP_004827
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PERK.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 17% glycerol with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK; EIF2AK3; PEK; PERK
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