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Peripherin Antibody

Peripherin Antibody

Cat no: 253203


Supplier: ABBIOTEC
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Peripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently,Porcineeripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also e, Xenopus/Amphibian,pressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments,Porcineeripherin is strongly up-regulated after nerve injury. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned a, Xenopus/Amphibian,ons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration.
Catalogue number: 253203
Reactivities: Human, Mouse, Rabbit
Applications: Immunofluorescence
Size: 0.1 ml
Accession: P21807
Antigen: Recombinant rat peripherin e, Xenopus/Amphibian,pressed in E. coli
Format: Each vial contains 0.1 ml IgG in PBS pH7.4 with 0.065% sodium azide. Antibody was purified by PEG precipitation.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 7C5
Additional info: Peripherin; Prph; Prph1