PerCP/Cy5.5 anti-human CD185 (CXCR5)

CXCR5 is a chemokine receptor which binds to CXCL13. CXCR5 is expressed in B cells and T folicular helper (TFH) cells (1). CXCR5 is required for migration of B cells to the follicular compartment in the spleen, lymph nodes, Peyer's patches, and tonsils, and normal maturation of primary follicle follicular dendritic cells (2, 3). CXCR5 and CXCL13 contribute in the B cell homing to Peyer's patches (4). In addition, T cell CXCR5 is required for germinal center response of normal magnitude (5).

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SPECIFICATIONS

Catalog Number

335001

Size

25 tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

TG2/CXCR5

Gene Id

643

Isotype

Mouse IgG2b, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 20 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * PerCP/Cy5.5 has a maximum absorption of 482 nm and 564 nm and a maximum emission of 690 nm.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

CXCR5, BLR1, MDR15

Regulatory Status

RUO