Presku: | AAP38756 |
Size: | 100 ug |
Weight: | 181kDa |
Gene: | 5178 |
Format: | Lyophilized powder |
Target: | PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells. |