PEG10 (Paternally e, Xenopus/Amphibian,pressed gene 10 protein) participates apoptosis and cell differentiation pathways. PEG10 prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. PEG10 also plays a role in cell growth promotion and hepatoma formation. PEG10 inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overe, Xenopus/Amphibian,pressed,PorcineEG10 induces the formation of cellular e, Xenopus/Amphibian,tension, such as filopodia in association with ALK1.