PE anti-mouse TCR Vbeta8.3

The Vbeta8.3 TCR is a variant of the TCR beta chain. It is expressed by a subset of peripheral blood T cells and is increased in response to some viral infections and tumors. T cells expressing the alpha/beta T cell receptor use clonally distributed TCRs to recognize cell-bound antigens such as peptide/MHC complexes and viral superantigens. The alpha/beta TCR is an oligomeric TCR complex composed of covalently bound alpha and beta chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3delta, gamma, epsilon, and ? chains. The 8C1 antibody has been used for the identification of T cells expressing Vbeta8.3 by flow cytometry.

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SPECIFICATIONS

Catalog Number

118605

Size

25 microg

Applications

FC

Hosts

Mouse

Reactivities

Mouse

Clone

8C1

Gene Id

21577

Isotype

Mouse IgG2a

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.2 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

T cell receptor Vb8.3

Regulatory Status

RUO