PE anti-mouse TCR Vbeta8.1, 8.2

Vbeta8 T cell receptor (TCR Vbeta8) subfamily has three members, Vbeta8.1, 8.2, and 8.3. These subfamily members are variants of the TCR beta chain that along with the TCR alpha chain forms the TCR heterodimer, responsible for the recognition of peptides presented by the MHC molecules. Murine Vbeta8+ T cells recognize the superantigen staphylococcal enterotoxin B (SEB); in vivo administration of SEB results in the negative selection of Vbeta8+ cells in the thymus. Vbeta8 is one of the most frequently found beta chains on the infiltrating T cells in the brain of mice with experimental autoimmune encephalomyelitis (EAE), and on the T cells response to Toxoplasma gondii.

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SPECIFICATIONS

Catalog Number

140103

Size

25 microg

Applications

FC

Hosts

Mouse

Reactivities

Mouse

Clone

MR5-2

Antigen

H-Y specific TH Clone OI6

Gene Id

21577

Isotype

Mouse IgG2a, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.2 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

Vbeta8 T-cell receptor, T cell receptor beta 8

Regulatory Status

RUO