PE anti-mouse/rat/human MCP-1

Monocyte chemotactic protein-1 (MCP-1) also known as monocyte chemotactic and activating factor (MCAF) was identified based on its ability to chemoattract monocytes. Subsequently, MCP-1 has also been found to regulate adhesion molecule expression and cytokine production in monocytes. MCP-1 is identical to the product of the JE gene, a PDGF inducible gene. MCP-1 is a member of the beta (C-C) chemokine subfamily, known as CCL2. The 2H5 antibody reacts with mouse, rat, and human MCP-1. The 2H5 antibody can neutralize the bioactivity of natural or recombinant MCP-1.

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SPECIFICATIONS

Catalog Number

505903

Size

25 microg

Applications

FC, ICC

Hosts

Ham

Reactivities

Hum, Mouse, Rat

Clone

2H5

Antigen

CHO-expressed, recombinant mouse MCP-1

Gene Id

20296,24770,6347

Isotype

Armenian Hamster IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining by flow cytometry, the suggested use of this product is ? 0.5 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.2 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

Monocyte chemoattractant protein-1, MCAF, JE, SCYA2, HC-11, P6, SMC-CF, CCL2

Regulatory Status

RUO