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PE anti-mouse CD49e

PE anti-mouse CD49e

Cat no: 103805

Supplier: BioLegend
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CD49e is a 135 kD protein, also known as alpha5 integrin or VLA-5 alpha chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin beta1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. The 5H10-27(MFR5) antibody has been shown to block CD49e mediated interactions and promote the in vitro stimulation of CD8+ T cells.
Catalogue number: 103805
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 50 microg
Clone: 5H10-27(MFR5)
Gene: 16402
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.2 mg/ml
Antigen: (C57BL/6 x A/J)F1 mouse mast cell line
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: alpha5 integrin, VLA-5 alpha chain, Integrin alpha5
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