PE anti-human IFN-gamma R beta chain

IFN-gamma R beta chain is a 65 kD type I transmembrane protein, also known as accessory factor (AF-1) or IFN-gammaRII. IFN-gamma receptor is composed of an IFN-gamma R alpha chain (CDw119) and a beta chain. They are members of the class II cytokine receptor family. The alpha chain is required for ligand binding and ligand trafficking to the cells and also plays some role in signal transduction. The beta chain is critical for delivering IFN-gamma mediated pleiotropic signals. IFN-gamma R beta chain is broadly expressed on a variety of cells at low levels and upregulated on some activated B cells.

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SPECIFICATIONS

Catalog Number

308504

Size

100 tests

Applications

FC

Hosts

Ham

Reactivities

Hum

Clone

2HUB-159

Antigen

soluable extracellular domains of the human IFN-gamma R beta chain

Gene Id

3459

Isotype

Hamster IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

IFN-gammaRbeta, IFNgammaAF-1

Regulatory Status

RUO