PE anti-human CD319 (CRACC)

CD319 is a single-pass type-1 335 aa transmembrane glycoprotein and expressed on NK cells, subsets of mature dendritic cells, activated B cells, cytotoxic lymphocytes but not in promyelocytic, B- or T-cell lines. Expression is high in spleen, lymph node, periperal blood leukocytes and lowest in bone marrow. Expression is in small intestine, stomach, appendix, lung and trachea. CD319 is tyrosine phosphorylated in activated NK cells and is associated with 19- and 39 kD proteins. CD319 has a homology with the CD2 family of receptors within the Ig superfamily. Some of the CD2 members stimulate cytotoxicity through the CD319 associated protein.

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SPECIFICATIONS

Catalog Number

331806

Size

100 tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

162.1

Antigen

CRACC-Human IgG1 fusion protein

Gene Id

57823

Isotype

Mouse IgG2b, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

CD2 like receptor activating cytotoxic cells, CD319, CS1, 19A24

Regulatory Status

RUO