Supplier:
Aviva Systems Biology IncorporatedPDE8A (phosphodiesterase 8A) Blocking Peptide (the C terminal of PDE8A)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP57753
Target
Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., MIM 2000). See MIM 171885.
Weight
88kDa
Gene Id
5151
Alternative Names
FLJ16150; HsT19550
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