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PDE6B (phosphodiesterase 6B, cGMP-specific, rod, beta ) Blocking Peptide (the N terminal of PDE6B)(100ug)

PDE6B (phosphodiesterase 6B, cGMP-specific, rod, beta ) Blocking Peptide (the N terminal of PDE6B)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PDE6B Antibody (ARP63581_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63581
Size: 100ug
Weight: 63kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names: CSNB3; CSNBAD2; PDEB; RP40; rd1
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