Supplier:
Aviva Systems Biology IncorporatedPDE6B (phosphodiesterase 6B, cGMP-specific, rod, beta ) Blocking Peptide (the C terminal of PDE6B)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP63580
Target
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Weight
63kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
CSNB3; CSNBAD2; PDEB; RP40; rd1
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